Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

To advance the systems approach in pharmacology, experimental models and computational methods need to be integrated from early drug discovery onward. Here, we propose outside‐in model development, a model identification technique to understand and predict the dynamics of a system without requiring...

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Detaylı Bibliyografya
Yayımlandı:CPT Pharmacometrics Syst Pharmacol
Asıl Yazarlar: Schulthess, Pascal, van Wijk, Rob C., Krekels, Elke H. J., Yates, James W. T., Spaink, Herman P., van der Graaf, Piet H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Perspective
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980533/
https://ncbi.nlm.nih.gov/pubmed/29693322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12297
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