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Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

To advance the systems approach in pharmacology, experimental models and computational methods need to be integrated from early drug discovery onward. Here, we propose outside‐in model development, a model identification technique to understand and predict the dynamics of a system without requiring...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:CPT Pharmacometrics Syst Pharmacol
Päätekijät: Schulthess, Pascal, van Wijk, Rob C., Krekels, Elke H. J., Yates, James W. T., Spaink, Herman P., van der Graaf, Piet H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980533/
https://ncbi.nlm.nih.gov/pubmed/29693322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12297
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