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Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

To advance the systems approach in pharmacology, experimental models and computational methods need to be integrated from early drug discovery onward. Here, we propose outside‐in model development, a model identification technique to understand and predict the dynamics of a system without requiring...

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Bibliografische gegevens
Gepubliceerd in:CPT Pharmacometrics Syst Pharmacol
Hoofdauteurs: Schulthess, Pascal, van Wijk, Rob C., Krekels, Elke H. J., Yates, James W. T., Spaink, Herman P., van der Graaf, Piet H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980533/
https://ncbi.nlm.nih.gov/pubmed/29693322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12297
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