Effects of mavacamten on Ca(2+) sensitivity of contraction as sarcomere length varied in human myocardium

BACKGROUND AND PURPOSE: Heart failure can reflect impaired contractile function at the myofilament level. In healthy hearts, myofilaments become more sensitive to Ca(2+) as cells are stretched. This represents a fundamental property of the myocardium that contributes to the Frank–Starling response,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Awinda, Peter O., Bishaw, Yemeserach, Watanabe, Marissa, Guglin, Maya A., Campbell, Kenneth S., Tanner, Bertrand C. W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707091/
https://ncbi.nlm.nih.gov/pubmed/32960449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15271
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak