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A new role for the synaptonemal complex in the regulation of meiotic recombination

Proper segregation during meiosis requires that homologs be connected by the combination of crossovers and sister chromatid cohesion. To generate crossovers, numerous double-strand breaks (DSBs) are introduced throughout the genome by the conserved Spo11 endonuclease. DSB formation and its repair ar...

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Publicat a:Genes Dev
Autor principal: Hollingsworth, Nancy M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706701/
https://ncbi.nlm.nih.gov/pubmed/33262143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345488.120
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