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A new role for the synaptonemal complex in the regulation of meiotic recombination

Proper segregation during meiosis requires that homologs be connected by the combination of crossovers and sister chromatid cohesion. To generate crossovers, numerous double-strand breaks (DSBs) are introduced throughout the genome by the conserved Spo11 endonuclease. DSB formation and its repair ar...

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Détails bibliographiques
Publié dans:Genes Dev
Auteur principal: Hollingsworth, Nancy M.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706701/
https://ncbi.nlm.nih.gov/pubmed/33262143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345488.120
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