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A new role for the synaptonemal complex in the regulation of meiotic recombination

Proper segregation during meiosis requires that homologs be connected by the combination of crossovers and sister chromatid cohesion. To generate crossovers, numerous double-strand breaks (DSBs) are introduced throughout the genome by the conserved Spo11 endonuclease. DSB formation and its repair ar...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteur: Hollingsworth, Nancy M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706701/
https://ncbi.nlm.nih.gov/pubmed/33262143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345488.120
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