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A new role for the synaptonemal complex in the regulation of meiotic recombination

Proper segregation during meiosis requires that homologs be connected by the combination of crossovers and sister chromatid cohesion. To generate crossovers, numerous double-strand breaks (DSBs) are introduced throughout the genome by the conserved Spo11 endonuclease. DSB formation and its repair ar...

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Detalhes bibliográficos
Publicado no:Genes Dev
Autor principal: Hollingsworth, Nancy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706701/
https://ncbi.nlm.nih.gov/pubmed/33262143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345488.120
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