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A new role for the synaptonemal complex in the regulation of meiotic recombination

Proper segregation during meiosis requires that homologs be connected by the combination of crossovers and sister chromatid cohesion. To generate crossovers, numerous double-strand breaks (DSBs) are introduced throughout the genome by the conserved Spo11 endonuclease. DSB formation and its repair ar...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autore principale: Hollingsworth, Nancy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706701/
https://ncbi.nlm.nih.gov/pubmed/33262143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345488.120
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