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Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice
Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identified in patients with autosomal dominant Parkinson’s disease...
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| Опубликовано в: : | Mol Brain |
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| Главные авторы: | , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7706192/ https://ncbi.nlm.nih.gov/pubmed/33261640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00704-3 |
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