Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice

Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identified in patients with autosomal dominant Parkinson’s disease...

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Publicado en:Mol Brain
Autores principales: Vanan, Sarivin, Zeng, Xiaoxia, Chia, Sook Yoong, Varnäs, Katarina, Jiang, Mei, Zhang, Ke, Saw, Wuan Ting, Padmanabhan, Parasuraman, Yu, Wei-Ping, Zhou, Zhi-Dong, Halldin, Christer, Gulyás, Balázs, Tan, Eng-King, Zeng, Li
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706192/
https://ncbi.nlm.nih.gov/pubmed/33261640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00704-3
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