VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

D620N mutation in the vacuolar protein sorting 35 ortholog (VPS35) gene causes late‐onset, autosomal dominant familial Parkinson's disease (PD) and contributes to idiopathic PD. However, how D620N mutation leads to PD‐related deficits in vivo remains unclear. In the present study, we thoroughly...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Niu, Mengyue, Zhao, Fanpeng, Bondelid, Karina, Siedlak, Sandra L., Torres, Sandy, Fujioka, Hisashi, Wang, Wenzhang, Liu, Jun, Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8135078/
https://ncbi.nlm.nih.gov/pubmed/33745227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13347
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