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Parkinson’s Disease-Associated Pathogenic VPS35 Mutation Causes Complex I Deficits

Defect in the complex I of the mitochondrial electron-transport chain is a characteristic of Parkinson’s disease (PD) which is thought to play a critical role in the disease pathogenesis. Mutations in vacuolar sorting protein 35 (VPS35) cause autosomal dominant PD and we recently demonstrated that p...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Zhou, Leping, Wang, Wenzhang, Hoppel, Charles, Liu, Jun, Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659972/
https://ncbi.nlm.nih.gov/pubmed/28765075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.07.032
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