Enhanced hyaluronan signaling and autophagy dysfunction by VPS35 D620N

The motor features of Parkinson’s disease (PD) result from the loss of dopaminergic (DA) neurons in the substantia nigra with autophagy dysfunction being closely linked to this disease. A PD-causing familial mutation in VPS35 (D620N) has been reported to inhibit autophagy. In order to identify signa...

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Publicado no:Neuroscience
Main Authors: Rahman, Abir A., Soto-Avellaneda, Alejandro, Jin, Hyun Yong, Stojkovska, Iva, Lai, Nathan K., Albright, Joshua E., Webb, Abby R., Oe, Emily, Valarde, Jacob P., Oxford, Alexandra E., Urquhart, Paige E., Wagner, Brandon, Brown, Connor, Amado, Isabella, Vasquez, Peyton, Lehning, Nicholas, Grozdanov, Veselin, Pu, Xinzhu, Danzer, Karin M., Morrison, Brad E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390708/
https://ncbi.nlm.nih.gov/pubmed/32540366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.06.009
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