Enhanced hyaluronan signaling and autophagy dysfunction by VPS35 D620N

The motor features of Parkinson’s disease (PD) result from the loss of dopaminergic (DA) neurons in the substantia nigra with autophagy dysfunction being closely linked to this disease. A PD-causing familial mutation in VPS35 (D620N) has been reported to inhibit autophagy. In order to identify signa...

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Bibliografski detalji
Izdano u:Neuroscience
Glavni autori: Rahman, Abir A., Soto-Avellaneda, Alejandro, Jin, Hyun Yong, Stojkovska, Iva, Lai, Nathan K., Albright, Joshua E., Webb, Abby R., Oe, Emily, Valarde, Jacob P., Oxford, Alexandra E., Urquhart, Paige E., Wagner, Brandon, Brown, Connor, Amado, Isabella, Vasquez, Peyton, Lehning, Nicholas, Grozdanov, Veselin, Pu, Xinzhu, Danzer, Karin M., Morrison, Brad E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390708/
https://ncbi.nlm.nih.gov/pubmed/32540366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.06.009
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