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Generation of universal and hypoimmunogenic human pluripotent stem cells

There is a need to store very large numbers of conventional human pluripotent stem cell (hPSC) lines for their off‐the‐shelf usage in stem cell therapy. Therefore, it is valuable to generate “universal” or “hypoimmunogenic” hPSCs with gene‐editing technology by knocking out or in immune‐related gene...

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Bibliographic Details
Published in:Cell Prolif
Main Authors: Ye, Qingsong, Sung, Tzu‐Cheng, Yang, Jen‐Ming, Ling, Qing‐Dong, He, Yan, Higuchi, Akon
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705897/
https://ncbi.nlm.nih.gov/pubmed/33174655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12946
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