Strategies for Genetically Engineering Hypoimmunogenic Universal Pluripotent Stem Cells

Despite progress in developing cell therapies, such as T cell or stem cell therapies to treat diseases, immunoincompatibility remains a major barrier to clinical application. Given the fact that a host's immune system may reject allogeneic transplanted cells, methods have been developed to gene...

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Bibliografiske detaljer
Udgivet i:iScience
Main Authors: Zhao, Wei, Lei, Anhua, Tian, Lin, Wang, Xudong, Correia, Cristina, Weiskittel, Taylor, Li, Hu, Trounson, Alan, Fu, Qiuli, Yao, Ke, Zhang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270609/
https://ncbi.nlm.nih.gov/pubmed/32502965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101162
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