Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

Autologous induced pluripotent stem cells (iPSCs) constitute an unlimited cell source for patient-specific cell-based organ repair strategies. However, their generation and subsequent differentiation into specific cells or tissues entail cell line-specific manufacturing challenges and form a lengthy...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Deuse, Tobias, Hu, Xiaomeng, Gravina, Alessia, Wang, Dong, Tediashvili, Grigol, De, Chandrav, Thayer, William O., Wahl, Angela, Garcia, J. Victor, Reichenspurner, Hermann, Davis, Mark M., Lanier, Lewis L., Schrepfer, Sonja
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419516/
https://ncbi.nlm.nih.gov/pubmed/30778232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0016-3
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