The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients

Pluripotent stem cells are promising candidates for cell-based regenerative therapies. To avoid rejection of transplanted cells, several approaches are being pursued to reduce immunogenicity of the cells or modulate the recipient's immune response. These include gene editing to reduce the antig...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Hu, Xiaomeng, Kueppers, Simon T., Kooreman, Nigel G., Gravina, Alessia, Wang, Dong, Tediashvili, Grigol, Schlickeiser, Stephan, Frentsch, Marco, Nikolaou, Christos, Thiel, Andreas, Marcus, Sivan, Fuchs, Sigrid, Velden, Joachim, Reichenspurner, Hermann, Volk, Hans-Dieter, Deuse, Tobias, Schrepfer, Sonja
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482111/
https://ncbi.nlm.nih.gov/pubmed/32723003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2019.0299
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