The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients

Pluripotent stem cells are promising candidates for cell-based regenerative therapies. To avoid rejection of transplanted cells, several approaches are being pursued to reduce immunogenicity of the cells or modulate the recipient's immune response. These include gene editing to reduce the antig...

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Udgivet i:Stem Cells Dev
Main Authors: Hu, Xiaomeng, Kueppers, Simon T., Kooreman, Nigel G., Gravina, Alessia, Wang, Dong, Tediashvili, Grigol, Schlickeiser, Stephan, Frentsch, Marco, Nikolaou, Christos, Thiel, Andreas, Marcus, Sivan, Fuchs, Sigrid, Velden, Joachim, Reichenspurner, Hermann, Volk, Hans-Dieter, Deuse, Tobias, Schrepfer, Sonja
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc., publishers 2020
Fag:
Original Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482111/
https://ncbi.nlm.nih.gov/pubmed/32723003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2019.0299
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