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APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival

Amyloid precursor protein (APP) is associated with both familial and sporadic forms of Alzheimer’s disease. Despite its importance, the role of APP family in neuronal function and survival remains unclear due to perinatal lethality exhibited by knockout mice lacking all three APP family members. Her...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Lee, Sang Hun, Kang, Jongkyun, Ho, Angela, Watanabe, Hirotaka, Bolshakov, Vadim Y., Shen, Jie
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704911/
https://ncbi.nlm.nih.gov/pubmed/32891188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.08.011
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