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Synaptic function of nicastrin in hippocampal neurons
Synaptic dysfunction is widely thought to play a key role in the pathogenesis of Alzheimer’s disease (AD). Presenilins, the major gene products involved in familial AD, are essential for short- and long-term synaptic plasticity in mature neurons as well as for the survival of cortical neurons during...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066509/ https://ncbi.nlm.nih.gov/pubmed/24889619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408554111 |
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