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End-stage renal disease reduces the expression of drug-metabolizing cytochrome P450s
BACKGROUND: End-stage renal disease is an irreversible status of kidney dysfunction that reduces both renal and non-renal drug clearance. Accumulation of uremic toxins seems to modify the activities of drug-metabolizing cytochrome P450 (CYP) enzymes. The aim of the present work was to refine gene ex...
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| Publicado no: | Pharmacol Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7704481/ https://ncbi.nlm.nih.gov/pubmed/32638224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-020-00127-w |
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