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Relevance of CYP2C9 Function in Valproate Therapy
BACKGROUND: Genetic polymorphisms of drug metabolizing enzymes can substantially modify the pharmacokinet-ics of a drug and eventually its efficacy or toxicity; however, inferring a patient’s drug metabolizing capacity merely from his or her genotype can lead to false prediction. Non-genetic host fa...
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| Publicado no: | Curr Neuropharmacol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6341495/ https://ncbi.nlm.nih.gov/pubmed/29119932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X15666171109143654 |
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