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Drug-induced liver graft toxicity caused by cytochrome P450 poor metabolism

AIMS: The drug-metabolizing capacity of transplanted liver highly influences drug efficacy or toxicity, particularly in the early postoperative period. The aim of our study was to predict therapeutic failures or severe adverse drug reactions by phenotyping for cytochrome P450 (P450) polymorphism res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kóbori, László, Kõhalmy, Krisztina, Porrogi, Pálma, Sárváry, Enikõ, Gerlei, Zsuzsa, Fazakas, János, Nagy, Péter, Járay, Jenõ, Monostory, Katalin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291242/
https://ncbi.nlm.nih.gov/pubmed/18070218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03056.x
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