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Patient subgroup identification for clinical drug development

Causal mechanism of relationship between the clinical outcome (efficacy or safety endpoints) and putative biomarkers, clinical baseline, and related predictors is usually unknown and must be deduced empirically from experimental data. Such relationships enable the development of tailored therapeutic...

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Podrobná bibliografie
Vydáno v:Stat Med
Hlavní autoři: Huang, Xin, Sun, Yan, Trow, Paul, Chatterjee, Saptarshi, Chakravartty, Arunava, Tian, Lu, Devanarayan, Viswanath
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704099/
https://ncbi.nlm.nih.gov/pubmed/28147447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7236
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