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Patient subgroup identification for clinical drug development

Causal mechanism of relationship between the clinical outcome (efficacy or safety endpoints) and putative biomarkers, clinical baseline, and related predictors is usually unknown and must be deduced empirically from experimental data. Such relationships enable the development of tailored therapeutic...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Huang, Xin, Sun, Yan, Trow, Paul, Chatterjee, Saptarshi, Chakravartty, Arunava, Tian, Lu, Devanarayan, Viswanath
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704099/
https://ncbi.nlm.nih.gov/pubmed/28147447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7236
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