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Patient subgroup identification for clinical drug development

Causal mechanism of relationship between the clinical outcome (efficacy or safety endpoints) and putative biomarkers, clinical baseline, and related predictors is usually unknown and must be deduced empirically from experimental data. Such relationships enable the development of tailored therapeutic...

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Détails bibliographiques
Publié dans:Stat Med
Auteurs principaux: Huang, Xin, Sun, Yan, Trow, Paul, Chatterjee, Saptarshi, Chakravartty, Arunava, Tian, Lu, Devanarayan, Viswanath
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704099/
https://ncbi.nlm.nih.gov/pubmed/28147447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7236
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