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Subgroup identification from randomized clinical trial data

We consider the problem of identifying a subgroup of patients who may have an enhanced treatment effect in a randomized clinical trial, and it is desirable that the subgroup be defined by a limited number of covariates. For this problem, the development of a standard, pre-determined strategy may hel...

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Detalhes bibliográficos
Main Authors: Foster, Jared C., Taylor, Jeremy M.G., Ruberg, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880775/
https://ncbi.nlm.nih.gov/pubmed/21815180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4322
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