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Crotonylation at Serine 46 Impairs p53 Activity
Post-translational modifications (PTMs) play pivotal roles in controlling the stability and activity of the tumor suppressor p53 in response to distinct stressors. Here we report an unexpected finding of a short chain fatty acid modification of p53 in human cells. Crotonic acid (CA) treatment induce...
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| 出版年: | Biochem Biophys Res Commun |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7703795/ https://ncbi.nlm.nih.gov/pubmed/32035620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.01.152 |
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