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Crotonylation at Serine 46 Impairs p53 Activity
Post-translational modifications (PTMs) play pivotal roles in controlling the stability and activity of the tumor suppressor p53 in response to distinct stressors. Here we report an unexpected finding of a short chain fatty acid modification of p53 in human cells. Crotonic acid (CA) treatment induce...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7703795/ https://ncbi.nlm.nih.gov/pubmed/32035620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.01.152 |
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