Recommendations for measuring HIV reservoir size in cure-directed clinical trials.

Therapeutic strategies are being clinically tested either to eradicate the latent HIV reservoir or to achieve virologic control in the absence of antiretroviral therapy (ART). Attaining this goal will require a consensus on how best to measure the levels of persistently-infected cells with the poten...

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Veröffentlicht in:Nat Med
Hauptverfasser: Abdel-Mohsen, Mohamed, Richman, Douglas, Siliciano, Robert F., Nussenzweig, Michel C., Howell, Bonnie, Martinez-Picado, Javier, Chomont, Nicolas, Bar, Katharine J, Yu, Xu G., Lichterfeld, Mathias, Alcami, Jose, Hazuda, Daria, Bushman, Frederic, Siliciano, Janet D., Betts, Michael R., Spivak, Adam M., Planelles, Vicente, Hahn, Beatrice H., Smith, David M, Ho, Ya-Chi, Buzon, Maria J., Gaebler, Christian, Paiardini, Mirko, Li, Qingsheng, Estes, Jacob D., Hope, Thomas J, Kostman, Jay, Mounzer, Karam, Caskey, Marina, Fox, Lawrence, Frank, Ian, Riley, James L, Tebas, Pablo, Montaner, Luis J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703694/
https://ncbi.nlm.nih.gov/pubmed/32895573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-1022-1
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