Recommendations for measuring HIV reservoir size in cure-directed clinical trials.

Therapeutic strategies are being clinically tested either to eradicate the latent HIV reservoir or to achieve virologic control in the absence of antiretroviral therapy (ART). Attaining this goal will require a consensus on how best to measure the levels of persistently-infected cells with the poten...

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Publicat a:Nat Med
Autors principals: Abdel-Mohsen, Mohamed, Richman, Douglas, Siliciano, Robert F., Nussenzweig, Michel C., Howell, Bonnie, Martinez-Picado, Javier, Chomont, Nicolas, Bar, Katharine J, Yu, Xu G., Lichterfeld, Mathias, Alcami, Jose, Hazuda, Daria, Bushman, Frederic, Siliciano, Janet D., Betts, Michael R., Spivak, Adam M., Planelles, Vicente, Hahn, Beatrice H., Smith, David M, Ho, Ya-Chi, Buzon, Maria J., Gaebler, Christian, Paiardini, Mirko, Li, Qingsheng, Estes, Jacob D., Hope, Thomas J, Kostman, Jay, Mounzer, Karam, Caskey, Marina, Fox, Lawrence, Frank, Ian, Riley, James L, Tebas, Pablo, Montaner, Luis J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703694/
https://ncbi.nlm.nih.gov/pubmed/32895573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-1022-1
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