Safety, Immune, and Antiviral Effects of Pegylated Interferon Alpha 2b Administration in Antiretroviral Therapy-Suppressed Individuals: Results of Pilot Clinical Trial

In the pilot NCT01935089 trial, we tested whether pegylated interferon alpha2b (Peg-IFN-α2b) with antiretroviral therapy (ART) was safe and could impact HIV and immune measures in blood and in gut-associated lymphoid tissue (GALT). Twenty HIV-1(+) ART-suppressed individuals received 1 μg/kg/week Peg...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Papasavvas, Emmanouil, Azzoni, Livio, Pagliuzza, Amélie, Abdel-Mohsen, Mohamed, Ross, Brian N., Fair, Matthew, Howell, Bonnie J., Hazuda, Daria J., Chomont, Nicolas, Li, Qingsheng, Mounzer, Karam, Kostman, Jay R., Tebas, Pablo, Montaner, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Clinical Trials/Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213011/
https://ncbi.nlm.nih.gov/pubmed/33323024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2020.0243
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