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Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages

Inflammasomes have been implicated in the detection and clearance of a variety of bacterial pathogens, but little is known about whether this innate sensing mechanism has any regulatory effect on the expression of stimulatory ligands by the pathogen. During infection with Salmonella and many other p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Akhade, Ajay Suresh, Atif, Shaikh M., Lakshmi, Bhavana S., Dikshit, Neha, Hughes, Kelly T., Qadri, Ayub, Subramanian, Naeha
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703570/
https://ncbi.nlm.nih.gov/pubmed/33177235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002747117
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