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Role of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis

Microglia are immune effector cells in the CNS and their activation, migration, and proliferation play crucial roles in brain injuries and diseases. We examined the role of iPLA(2) in the regulation of microglia chemotaxis toward ADP. Inhibition of iPLA(2) by BEL or iPLA(2) knock-down exerted a sign...

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Detalhes bibliográficos
Main Authors: Lee, Sang-Hyun, Schneider, Claus, Higdon, Ashlee N, Darley-Usmar, Victor M., Chung, Chang Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115410/
https://ncbi.nlm.nih.gov/pubmed/21438970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01195.x
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