Role of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis

Microglia are immune effector cells in the CNS and their activation, migration, and proliferation play crucial roles in brain injuries and diseases. We examined the role of iPLA(2) in the regulation of microglia chemotaxis toward ADP. Inhibition of iPLA(2) by BEL or iPLA(2) knock-down exerted a sign...

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Main Authors: Lee, Sang-Hyun, Schneider, Claus, Higdon, Ashlee N, Darley-Usmar, Victor M., Chung, Chang Y.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115410/
https://ncbi.nlm.nih.gov/pubmed/21438970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01195.x
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