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Resolving the 3D landscape of transcription-linked mammalian chromatin folding

Whereas folding of genomes at the large scale of epigenomic compartments and topologically associating domains is now relatively well understood, how chromatin is folded at finer scales remains largely unexplored in mammals. Here, we overcome some limitations of conventional 3C-based methods by usin...

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Vydáno v:Mol Cell
Hlavní autoři: Hsieh, Tsung-Han S., Cattoglio, Claudia, Slobodyanyuk, Elena, Hansen, Anders S., Rando, Oliver J., Tjian, Robert, Darzacq, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703524/
https://ncbi.nlm.nih.gov/pubmed/32213323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.002
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