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Src Mediates Epigallocatechin-3-O-Gallate-Elicited Acid Sphingomyelinase Activation

Epigallocatechin-3-O-gallate (EGCG) is one of the major bioactive compounds known to be present in green tea. We previously reported that EGCG shows selective toxicity through activation of the protein kinase B (Akt)/cyclic guanosine monophosphate (cGMP)/acid sphingomyelinase (ASM) axis via targetin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Kumazoe, Motofumi, Kadomatsu, Mai, Bae, Jaehoon, Otsuka, Yushi, Fujimura, Yoshinori, Tachibana, Hirofumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700551/
https://ncbi.nlm.nih.gov/pubmed/33238540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25225481
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