Epigallocatechin-3-O-gallate up-regulates microRNA-let-7b expression by activating 67-kDa laminin receptor signaling in melanoma cells

MicroRNAs (miRNAs) are non-coding RNAs involved in various biological processes by regulating their target genes. Green tea polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) inhibits melanoma tumor growth by activating 67-kDa laminin receptor (67LR) signaling. To examine the effect of EGCG on miRNA...

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Publicat a:Sci Rep
Autors principals: Yamada, Shuhei, Tsukamoto, Shuntaro, Huang, Yuhui, Makio, Akiko, Kumazoe, Motofumi, Yamashita, Shuya, Tachibana, Hirofumi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709792/
https://ncbi.nlm.nih.gov/pubmed/26754091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19225
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