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Src Mediates Epigallocatechin-3-O-Gallate-Elicited Acid Sphingomyelinase Activation

Epigallocatechin-3-O-gallate (EGCG) is one of the major bioactive compounds known to be present in green tea. We previously reported that EGCG shows selective toxicity through activation of the protein kinase B (Akt)/cyclic guanosine monophosphate (cGMP)/acid sphingomyelinase (ASM) axis via targetin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kumazoe, Motofumi, Kadomatsu, Mai, Bae, Jaehoon, Otsuka, Yushi, Fujimura, Yoshinori, Tachibana, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700551/
https://ncbi.nlm.nih.gov/pubmed/33238540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25225481
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