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Stress-Based High-Throughput Screening Assays to Identify Inhibitors of Cell Envelope Biogenesis

The structural integrity of the Gram-negative cell envelope is guarded by several stress responses, such as the σ(E), Cpx and Rcs systems. Here, we report on assays that monitor these responses in E. coli upon addition of antibacterial compounds. Interestingly, compromised peptidoglycan synthesis, o...

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Bibliografiska uppgifter
I publikationen:Antibiotics (Basel)
Huvudupphovsmän: Steenhuis, Maurice, ten Hagen-Jongman, Corinne M., van Ulsen, Peter, Luirink, Joen
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698014/
https://ncbi.nlm.nih.gov/pubmed/33202774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9110808
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