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Stress-Based High-Throughput Screening Assays to Identify Inhibitors of Cell Envelope Biogenesis
The structural integrity of the Gram-negative cell envelope is guarded by several stress responses, such as the σ(E), Cpx and Rcs systems. Here, we report on assays that monitor these responses in E. coli upon addition of antibacterial compounds. Interestingly, compromised peptidoglycan synthesis, o...
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| Udgivet i: | Antibiotics (Basel) |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7698014/ https://ncbi.nlm.nih.gov/pubmed/33202774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9110808 |
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