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Stress-Based High-Throughput Screening Assays to Identify Inhibitors of Cell Envelope Biogenesis

The structural integrity of the Gram-negative cell envelope is guarded by several stress responses, such as the σ(E), Cpx and Rcs systems. Here, we report on assays that monitor these responses in E. coli upon addition of antibacterial compounds. Interestingly, compromised peptidoglycan synthesis, o...

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Dades bibliogràfiques
Publicat a:Antibiotics (Basel)
Autors principals: Steenhuis, Maurice, ten Hagen-Jongman, Corinne M., van Ulsen, Peter, Luirink, Joen
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698014/
https://ncbi.nlm.nih.gov/pubmed/33202774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9110808
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