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Stress-Based High-Throughput Screening Assays to Identify Inhibitors of Cell Envelope Biogenesis

The structural integrity of the Gram-negative cell envelope is guarded by several stress responses, such as the σ(E), Cpx and Rcs systems. Here, we report on assays that monitor these responses in E. coli upon addition of antibacterial compounds. Interestingly, compromised peptidoglycan synthesis, o...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Steenhuis, Maurice, ten Hagen-Jongman, Corinne M., van Ulsen, Peter, Luirink, Joen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698014/
https://ncbi.nlm.nih.gov/pubmed/33202774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9110808
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