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Stress-Based High-Throughput Screening Assays to Identify Inhibitors of Cell Envelope Biogenesis

The structural integrity of the Gram-negative cell envelope is guarded by several stress responses, such as the σ(E), Cpx and Rcs systems. Here, we report on assays that monitor these responses in E. coli upon addition of antibacterial compounds. Interestingly, compromised peptidoglycan synthesis, o...

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書誌詳細
出版年:Antibiotics (Basel)
主要な著者: Steenhuis, Maurice, ten Hagen-Jongman, Corinne M., van Ulsen, Peter, Luirink, Joen
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698014/
https://ncbi.nlm.nih.gov/pubmed/33202774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9110808
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