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Comparing autotransporter β-domain configurations for their capacity to secrete heterologous proteins to the cell surface

Monomeric autotransporters have been extensively used for export of recombinant proteins to the cell surface of Gram-negative bacteria. A bottleneck in the biosynthesis of such constructs is the passage of the outer membrane, which is facilitated by the β-domain at the C terminus of an autotransport...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Jong, Wouter S. P., Schillemans, Maaike, ten Hagen-Jongman, Corinne M., Luirink, Joen, van Ulsen, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802855/
https://ncbi.nlm.nih.gov/pubmed/29415042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191622
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