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Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability

SIMPLE SUMMARY: Microsatellite instability (MSI) has been detected in multiple types of gynecologic cancers. MSI is linked to mutations in mismatch repair (MMR) genes that cause mismatch repair deficit (dMMR) in human cells. Discovery of new therapeutic approaches are needed especially for treatment...

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Publicat a:Cancers (Basel)
Autors principals: Deshpande, Madhura, Romanski, Phillip A., Rosenwaks, Zev, Gerhardt, Jeannine
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697596/
https://ncbi.nlm.nih.gov/pubmed/33182707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113319
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