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Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability

SIMPLE SUMMARY: Microsatellite instability (MSI) has been detected in multiple types of gynecologic cancers. MSI is linked to mutations in mismatch repair (MMR) genes that cause mismatch repair deficit (dMMR) in human cells. Discovery of new therapeutic approaches are needed especially for treatment...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Deshpande, Madhura, Romanski, Phillip A., Rosenwaks, Zev, Gerhardt, Jeannine
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697596/
https://ncbi.nlm.nih.gov/pubmed/33182707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113319
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