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Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability

SIMPLE SUMMARY: Microsatellite instability (MSI) has been detected in multiple types of gynecologic cancers. MSI is linked to mutations in mismatch repair (MMR) genes that cause mismatch repair deficit (dMMR) in human cells. Discovery of new therapeutic approaches are needed especially for treatment...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Deshpande, Madhura, Romanski, Phillip A., Rosenwaks, Zev, Gerhardt, Jeannine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697596/
https://ncbi.nlm.nih.gov/pubmed/33182707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113319
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