The degree of microsatellite instability predicts response to PD-1 blockade immunotherapy in mismatch repair-deficient/microsatellite instability-high colorectal cancers

The development of programmed cell death-1 inhibitor (PD-1) has shed light on the treatment of tumors with deficiencies in DNA mismatch repair system or microsatellite instability (dMMR/MSI). However, predicting the subset in this group that will benefit from PD-1 blockade remains a challenge. In th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Exp Hematol Oncol
Hauptverfasser: Wang, Qiao-Xuan, Qu, Chun-Hua, Gao, Yuan-Hong, Ding, Pei-Rong, Yun, Jing-Ping, Xie, Dan, Cai, Mu-Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Letter to the Editor
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784284/
https://ncbi.nlm.nih.gov/pubmed/33397433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00193-z
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