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Blood–Brain Barrier Modulation to Improve Glioma Drug Delivery

The blood–brain barrier (BBB) is formed by brain microvascular endothelial cells that are sealed by tight junctions, making it a significant obstacle for most brain therapeutics. The poor BBB penetration of newly developed therapeutics has therefore played a major role in limiting their clinical suc...

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Detalles Bibliográficos
Publicado en:Pharmaceutics
Main Authors: Luo, Huilong, Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697580/
https://ncbi.nlm.nih.gov/pubmed/33198244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111085
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