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Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier
Biologics are an emerging class of medicines with substantial promise to treat neurological disorders such as Alzheimer’s disease, stroke and multiple sclerosis. However, the blood-brain barrier (BBB) presents a formidable obstacle that appreciably limits brain uptake and hence, therapeutic potentia...
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| Publicat a: | Annu Rev Pharmacol Toxicol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5051266/ https://ncbi.nlm.nih.gov/pubmed/25340933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010814-124852 |
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