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Targeted delivery of proteins across the blood–brain barrier

Treatment of many neuronal degenerative disorders will require delivery of a therapeutic protein to neurons or glial cells across the whole CNS. The presence of the blood–brain barrier hampers the delivery of these proteins from the blood, thus necessitating a new method for delivery. Receptors on t...

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Bibliographic Details
Main Authors: Spencer, Brian J., Verma, Inder M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857226/
https://ncbi.nlm.nih.gov/pubmed/17463083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702170104
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