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Blood–Brain Barrier Modulation to Improve Glioma Drug Delivery

The blood–brain barrier (BBB) is formed by brain microvascular endothelial cells that are sealed by tight junctions, making it a significant obstacle for most brain therapeutics. The poor BBB penetration of newly developed therapeutics has therefore played a major role in limiting their clinical suc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Luo, Huilong, Shusta, Eric V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697580/
https://ncbi.nlm.nih.gov/pubmed/33198244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111085
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