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Stereotactic modulation of blood-brain barrier permeability to enhance drug delivery

Drug delivery in the CNS is limited by endothelial tight junctions forming the impermeable blood-brain barrier. The development of new treatment paradigms has previously been hampered by the restrictiveness of the blood-brain barrier to systemically administered therapeutics. With recent advances in...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Appelboom, Geoff, Detappe, Alexandre, LoPresti, Melissa, Kunjachan, Sijumon, Mitrasinovic, Stefan, Goldman, Serge, Chang, Steve D., Tillement, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744238/
https://ncbi.nlm.nih.gov/pubmed/27407134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now137
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