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Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

The blood–brain barrier (BBB) is a major obstacle for drug delivery to the brain. To seek for in vitro BBB models that are more accessible than animals for investigating drug transport across the BBB, we compared four in vitro cultured cell models: endothelial monoculture (bEnd3 cell line), cocultur...

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Detalhes bibliográficos
Main Authors: Li, Guanglei, Simon, Melissa J., Cancel, Limary M., Shi, Zhong-Dong, Ji, Xinying, Tarbell, John M., Morrison, Barclay, Fu, Bingmei M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157339/
https://ncbi.nlm.nih.gov/pubmed/20361260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-010-0023-5
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