Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

Excessive levels of saturated fatty acids are toxic to cells, although the basis for this lipotoxicity remains incompletely understood. Here we analyzed the transcriptome, lipidome, and genetic interactions of human leukemia cells exposed to palmitate. Palmitate treatment increased saturated glycero...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Piccolis, Manuele, Bond, Laura M., Kampmann, Martin, Pulimeno, Pamela, Chitraju, Chandramojan, Jayson, Christina B.K., Vaites, Laura P., Boland, Sebastian, Lai, Zon Weng, Gabriel, Katlyn R., Elliott, Shane D., Paulo, Joao A., Harper, J. Wade, Weissman, Jonathan S., Walther, Tobias C., Farese, Robert V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696670/
https://ncbi.nlm.nih.gov/pubmed/30846318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.036
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