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Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity
Obesity is tightly linked to hepatic steatosis and insulin resistance. One feature of this association is the paradox of selective insulin resistance: insulin fails to suppress hepatic gluconeogenesis but activates lipid synthesis in the liver. How lipid accumulation interferes selectively with some...
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| Publicado no: | Mol Cell Proteomics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5930403/ https://ncbi.nlm.nih.gov/pubmed/29414761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000560 |
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