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Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity

Obesity is tightly linked to hepatic steatosis and insulin resistance. One feature of this association is the paradox of selective insulin resistance: insulin fails to suppress hepatic gluconeogenesis but activates lipid synthesis in the liver. How lipid accumulation interferes selectively with some...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cell Proteomics
मुख्य लेखकों: Li, Zhihuan, Lai, Zon Weng, Christiano, Romain, Gazos-Lopes, Felipe, Walther, Tobias C., Farese, Robert V.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Biochemistry and Molecular Biology 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930403/
https://ncbi.nlm.nih.gov/pubmed/29414761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000560
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