Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice

Nonalcoholic fatty liver disease (NAFLD) is characterized by excess lipid accumulation in hepatocytes and represents a huge public health problem owing to its propensity to progress to nonalcoholic steatohepatitis, fibrosis, and liver failure. The lipids stored in hepatic steatosis (HS) are primaril...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Gluchowski, Nina L., Gabriel, Katlyn R., Chitraju, Chandramohan, Bronson, Roderick T., Mejhert, Niklas, Boland, Sebastian, Wang, Kun, Lai, Zon Weng, Farese, Robert V., Walther, Tobias C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893913/
https://ncbi.nlm.nih.gov/pubmed/31081165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30765
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